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`mariner` is an R/Bioconductor package for exploring Hi-C data. It enables users to flexibly manipulate, extract, and aggregate chromatin interaction data quickly and efficiently.

Details

Key Features:

  • Manipulating Paired Ranges - Convert, bin, and shift paired genomic ranges.

  • Clustering & Merging Interactions - Group nearby interactions and select one as representative.

  • Extracting & Aggregating Interactions - Pull Hi-C pixels or matrices, then aggregate by files or interactions.

  • Calculating Loop Enrichment - Determine loop enrichment to local background with selection functions to flexibility select foreground and background.

For more details on the features of `mariner`, read the vignette: `browseVignettes(package="mariner")`

Author

Maintainer: Eric Davis ericscottdavis@outlook.com (ORCID)

Authors: