`mariner` is an R/Bioconductor package for exploring Hi-C data. It enables users to flexibly manipulate, extract, and aggregate chromatin interaction data quickly and efficiently.
Details
Key Features:
Manipulating Paired Ranges - Convert, bin, and shift paired genomic ranges.
Clustering & Merging Interactions - Group nearby interactions and select one as representative.
Extracting & Aggregating Interactions - Pull Hi-C pixels or matrices, then aggregate by files or interactions.
Calculating Loop Enrichment - Determine loop enrichment to local background with selection functions to flexibility select foreground and background.
For more details on the features of `mariner`, read the vignette: `browseVignettes(package="mariner")`
Author
Maintainer: Eric Davis ericscottdavis@outlook.com (ORCID)
Authors:
Sarah Parker smp3800@gmail.com (ORCID)